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Thromb Haemost 1975; 33(03): 547-552
DOI: 10.1055/s-0038-1647848
Original Article
Schattauer GmbH

Performances of an Artificial Reagent for the One-stage Factor IX Assay

L Meunier
1   Center for Haemophilic Children, Croix-Rouge Française, La Queue-les-Yvelines, the Unit 56 of the I.N.S.E.R.M. and the National Blood Center 75015 Paris, France
,
J. P Allain
1   Center for Haemophilic Children, Croix-Rouge Française, La Queue-les-Yvelines, the Unit 56 of the I.N.S.E.R.M. and the National Blood Center 75015 Paris, France
,
D Frommel
1   Center for Haemophilic Children, Croix-Rouge Française, La Queue-les-Yvelines, the Unit 56 of the I.N.S.E.R.M. and the National Blood Center 75015 Paris, France
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Publikationsverlauf

Received 07. Oktober 1974

Accepted 12. Februar 1975

Publikationsdatum:
02. Juli 2018 (online)

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Summary

A mixture of adsorbed normal human plasma and chicken plasma was prepared as reagent for factor IX measurement using a one-stage method. The substrate was found to be specific for factor IX. Its performances tested on samples displaying factor IX activity ranging from <l%–2,500% compared favorably with those obtained when using the plasma of severe haemophilia B patients as substrate.